Microdosing
Subtle shifts. Big questions. What happens when you redesign your baseline?
Microdosing — the practice of taking sub-perceptual doses of psychedelics (usually LSD or psilocybin) — has become a creative world buzzword. It's been linked to sharper focus, enhanced problem-solving, emotional resilience, and even mood stability.
But despite the headlines, the science is still catching up. And the experience? Highly personal, often overhyped, and still legally risky in most places.
Let’s zoom out — and in.
What Is Microdosing, Exactly?
Microdosing typically means taking about 1/10th to 1/20th of a standard psychedelic dose, just enough to notice something, but not enough to alter your sense of self, time, or space.
Common substances:
LSD (usually 5–20μg)
Psilocybin (usually 0.1–0.3g of dried mushrooms)
Common schedules:
Fadiman protocol (1 day on, 2 days off)
Stamets stack (includes Lion’s Mane + niacin)
Intuitive dosing (user-defined rhythm based on need or feel
Reported Benefits (Anecdotal + Emerging Research)
Enhanced focus or flow states
Mood elevation, reduced anxiety
Feeling of groundedness
Increased sensory awareness
More patient or present in daily interactions
What to Be Cautious About
Tolerance and diminishing returns: Some users report benefits fade after a few weeks.
Relying on it: Microdosing shouldn't become the only way you feel "productive."
Underlying conditions: For people with bipolar, anxiety disorders, or psychiatric sensitivity, even low doses can sometimes destabilize rather than uplift.
Lack of regulation: Dosing consistency is hard to control outside of research settings.
Listen: Microdosing with Tiffany Hurd
In this episode, we talk with Tiffany Hurd — microdosing consultant, coach, speaker, and business leadership advisor who has supported over 250 individuals and their teams through microdosing experiences.
Microdosing Protocols
Here’s a quick look at notable or emerging microdosing protocols:
1. Fadiman Protocol (classic)
Schedule: 1 day on, 2 days off
Cycle: Repeat every 3 days
Why: Allows observation of effects on and after dosing day
Good for: Beginners, people seeking creativity or mood lift without overstimulation
2. Stamets Stack
Schedule: 4 days on, 3 days off (e.g. Mon–Thu)
Supplements: Psilocybin + Lion’s Mane + Niacin
Why: Based on neuroplasticity and mycelial health theory
Good for: Long-term personal development, neurogenesis interest
3. Intuitive Dosing
Schedule: Self-guided
Why: Emphasizes responsiveness, somatic awareness
Good for: Experienced users, those integrating somatics or meditation
4. Every Other Day Protocol
Schedule: 1 day on, 1 day off
Why: Simpler to follow, more consistent exposure
Risks: May lead to tolerance quicker; less integration time
Good for: Short-term creative sprint or mental health trial
5. Microdosing for Mental Health (Research-Based)
Used in clinical studies (e.g. Beckley Foundation, Imperial College trials)
Schedule: Often 2x/week or every third day
Dosing: Precise, standardized (e.g., 10µg LSD or 0.2g psilocybin)
Why: Designed for controlled symptom tracking
Good for: People participating in structured protocols with medical oversight
6. Productivity Protocols (Silicon Valley-style)
Schedule: 2–3 times per week, aligned with “high-focus” days
Stacked with: Nootropics, caffeine, biohacking routines
Why: Maximize output, often paired with design sprints
Caution: Can reinforce hustle culture mindset and burnout
Good for: Those exploring creative flow but willing to reflect critically
Design-Centric Tips for Exploring Microdosing (If You Choose To)
Track patterns, not perfection: Journal or log your mental, emotional, and creative patterns — not just outcomes.
Stack with intention, not pressure: If using supplements like Lion’s Mane or niacin, pay attention to how your body responds.
Do one thing at a time: Don’t start microdosing and change your diet and try a new workout regime. Isolate the variable.
Build in breaks: Reset your baseline. See what’s really changed.
Diving deeper:
Microdosing Institute — comprehensive global education
Microdosing Collective — educational webinars and in-person activations
Microdosing for Health, Healing, and Enhanced Performance — a new book by James Fadiman PhD and Jordan Gruber JD
Microdosing is not a shortcut to your best self. But for some, it’s a subtle lens adjustment — a way to see the familiar with fresh eyes.